Potential diagnostic value of miRNAs in sexually transmitted infections

•We offer a detailed elucidation of diagnostic value of miRNAs in the context of sexually transmitted infections (STIs) while also recognizing its limitations.•A more detailed description of miRNA is provided.•The article is relatively lengthy and maintains a clear logical structure. MiRNAs are smal...

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Bibliographic Details
Published in:Gene 2024-02, Vol.895, p.147992-147992, Article 147992
Main Authors: Peng, Yunchi, Xiao, Shuangwen, Zuo, Wei, Xie, Yafeng, Xiao, Yongjian
Format: Article
Language:English
Subjects:
Biomarker
Chlamydia
Diagnosis
HIV
HIV Infections
HPV
HSV
Humans
MicroRNAs - genetics
miRNA
Sexually Transmitted Diseases - diagnosis
Sexually Transmitted Diseases - genetics
STIs
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Summary:•We offer a detailed elucidation of diagnostic value of miRNAs in the context of sexually transmitted infections (STIs) while also recognizing its limitations.•A more detailed description of miRNA is provided.•The article is relatively lengthy and maintains a clear logical structure. MiRNAs are small endogenous non-coding RNAs that have been demonstrated to be involved in post-transcriptional gene silencing, regulating a number of metabolic functions in the human body, including immune response, cellular physiology, organ development, angiogenesis, signaling, and other aspects. As popular molecules that have been studied in previous years, given their extensive regulatory functions, miRNAs hold considerable promise as non-invasive biomarkers. Sexually transmitted infections(STIs) are still widespread and have an adverse effect on individuals, communities, and society worldwide. miRNAs in the regulatory networks are generally involved in their molecular processes of formation and development. In this review, we discuss the value of miRNAs for the diagnosis of STIs.
ISSN:0378-1119
1879-0038
DOI:10.1016/j.gene.2023.147992