Impact of Hypertension on Left Ventricular Geometry and Diastolic Function in Africa: Results from the Population-Based TAnve Health (TAHES) Cohort Study

High blood pressure leads to morphologic changes and functional alterations of the myocardial structure. Transthoracic echocardiography is of great clinical interest to evaluate these alterations, using reference values proposed by the American Society of Echocardiography/European Association of Car...

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Bibliographic Details
Published in:The American journal of cardiology 2024-01, Vol.211, p.275-281
Main Authors: Vandroux, David, Aboyans, Victor, Houehanou, Yessito Corine, Chastaingt, Lucie, Saka, Dominique, Sonou, Arnaud, Amidou, Salmane, Houinato, Dismand, Preux, Pierre Marie, Magne, Julien, Lacroix, Philippe
Format: Article
Language:English
Subjects:
Abnormalities
Antihypertensives
Blood pressure
Body mass index
Cardiovascular diseases
Cohort analysis
Cohort Studies
Confidence intervals
Diabetes mellitus
Diastole - physiology
Doppler effect
Echocardiography
Ethnic factors
Female
Geometry
Heart
Humans
Hypertension
Male
Middle Aged
Population
Population studies
Prospective Studies
Regression analysis
Relaxation time
Ventricle
Ventricular Dysfunction, Left - complications
Ventricular Dysfunction, Left - diagnostic imaging
Ventricular Dysfunction, Left - epidemiology
Ventricular Function, Left - physiology
Womens health
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Summary:High blood pressure leads to morphologic changes and functional alterations of the myocardial structure. Transthoracic echocardiography is of great clinical interest to evaluate these alterations, using reference values proposed by the American Society of Echocardiography/European Association of Cardiovascular Imaging, largely based on studies in Caucasian Whites. We aimed to assess the impact of hypertension on echocardiographic parameters in a sub-Saharan African community, using ethnic-specific reference values. This study is part of the TAnve HEalth Study, a population-based prospective cohort study initiated in 2015 in the district of Tanve, Republic of Benin. Hypertension was defined as systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure ≥90 mm Hg and/or currently taking antihypertensive medications. All participants had a transthoracic echocardiography. The patterns of diastolic dysfunction and left ventricular (LV) geometry were defined from 486 subjects in the cohort, free from cardiovascular disease, diabetes, and hypertension. Of all participants, 318 (65% women, median age 48 years) had hypertension. Systolic blood pressure correlated significantly (p
ISSN:0002-9149
1879-1913
1879-1913
DOI:10.1016/j.amjcard.2023.10.087