Pregnancy intention in relation to maternal and neonatal outcomes in women with versus without psychiatric diagnoses

Background Studies have identified adverse maternal and neonatal outcomes for women with psychiatric disorders. Additionally, psychiatric disorders may pose an increased risk for unintended pregnancies (UPs) which in turn may also impact negatively on outcomes. The present study aims to compare the...

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Published in:Acta psychiatrica Scandinavica 2024-02, Vol.149 (2), p.110-123
Main Authors: Schonewille, Noralie N., Jonkman, Nini H., Kempen, Anne A. M. W., Pampus, Maria G., Heuvel, Odile A., Broekman, Birit F. P.
Format: Article
Language:English
Subjects:
Addictions
Adolescent
Apgar score
Birth weight
Diabetes mellitus
Female
Gestational Age
Humans
Infant, Newborn
Intention
Mental disorders
Mental Disorders - epidemiology
Neonates
Patients
Pregnancy
Pregnancy complications
Pregnancy Outcome - epidemiology
pregnancy outcomes
pregnancy planning
psychiatry
Regression analysis
Retrospective Studies
unintended pregnancies
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Summary:Background Studies have identified adverse maternal and neonatal outcomes for women with psychiatric disorders. Additionally, psychiatric disorders may pose an increased risk for unintended pregnancies (UPs) which in turn may also impact negatively on outcomes. The present study aims to compare the incidence of UPs in women with versus without current/past psychiatric diagnoses and investigates whether psychiatric history modifies the relation between delivery outcomes in women with and without UPs. Methods A retrospective cohort was compiled of women who gave birth in a large hospital in Amsterdam, the Netherlands. Women ≥18 years old with singleton pregnancies and birth registrations in the electronic patient file during January 1, 2015 to March 1, 2020 were included. Patient characteristics (including pregnancy intention and psychiatric history), maternal (gestational diabetes, mode of delivery) and neonatal outcomes (e.g., gestational age [GA], birthweight and Apgar scores) were registered by health care providers in hospital charts. Incidence of UPs was compared between women with versus without current/past psychiatric diagnoses. Maternal and neonatal outcomes were compared between women with versus without UPs with linear or logistic regression models adjusted for relevant confounders with an interaction term for UP with current/past psychiatric diagnoses. Results We included 1219 women with and 1093 women without current/past psychiatric diagnoses. Current/past psychiatric diagnoses were significantly associated with UPs after adjustment for confounders (39.0% vs. 29.6%, OR 1.56, CI 1.23–2.00, p 
ISSN:0001-690X
1600-0447
1600-0447
DOI:10.1111/acps.13625