White blood cell and platelet distribution widths are associated with hypertension: data mining approaches

In this paper, we are going to investigate the association between Hypertension (HTN) and routine hematologic indices in a cohort of Iranian adults. The data were obtained from a total population of 9704 who were aged 35-65 years, a prospective study was designed. The association between hematologic...

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Published in:Hypertension research 2024-02, Vol.47 (2), p.515-528
Main Authors: Mansoori, Amin, Farizani Gohari, Narjes Sadat, Etemad, Leila, Poudineh, Mohadeseh, Ahari, Rana Kolahi, Mohammadyari, Fatemeh, Azami, Mobin, Rad, Elias Sadooghi, Ferns, Gordon, Esmaily, Habibollah, Ghayour Mobarhan, Majid
Format: Article
Language:English
Subjects:
Adult
Cohort Studies
Female
Humans
Hypertension
Iran - epidemiology
Leukocytes
Prospective Studies
Risk Factors
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Summary:In this paper, we are going to investigate the association between Hypertension (HTN) and routine hematologic indices in a cohort of Iranian adults. The data were obtained from a total population of 9704 who were aged 35-65 years, a prospective study was designed. The association between hematologic factors and HTN was assessed using logistic regression (LR) analysis and a decision tree (DT) algorithm. A total of 9704 complete datasets were analyzed in this cohort study (N = 3070 with HTN [female 62.47% and male 37.52%], N = 6634 without HTN [female 58.90% and male 41.09%]). Several variables were significantly different between the two groups, including age, smoking status, BMI, diabetes millitus, high sensitivity C-reactive protein (hs-CRP), uric acid, FBS, total cholesterol, HGB, LYM, WBC, PDW, RDW, RBC, sex, PLT, MCV, SBP, DBP, BUN, and HCT (P 
ISSN:0916-9636
1348-4214
DOI:10.1038/s41440-023-01472-y