Confocal Microscopy, Anterior Segment Optical Coherence Tomography and Clinical Findings in a Non-Granulomatous Uveitis Case for Mpox Infection

To report a rare case of non-granulomatous anterior uveitis (clinical, IVCM in vivo confocal microscopy, and anterior optical coherence tomography (OCT) findings) in a non-immunosuppressed patient with mpox infection. A 24-year-old male was consulted for bilateral ocular pain, red eye, itchiness, an...

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Bibliographic Details
Published in:Ocular immunology and inflammation 2024-10, Vol.32 (8), p.1901-1903
Main Authors: Avila, Marcel Y, Gallego-Suarez, Laura J
Format: Article
Language:English
Subjects:
Anterior Eye Segment - diagnostic imaging
Anterior Eye Segment - pathology
Glucocorticoids - therapeutic use
Humans
Male
Microscopy, Confocal
Tomography, Optical Coherence - methods
Uveitis, Anterior - diagnosis
Uveitis, Anterior - drug therapy
Young Adult
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Summary:To report a rare case of non-granulomatous anterior uveitis (clinical, IVCM in vivo confocal microscopy, and anterior optical coherence tomography (OCT) findings) in a non-immunosuppressed patient with mpox infection. A 24-year-old male was consulted for bilateral ocular pain, red eye, itchiness, and mucoid discharge. In his left eye, multiple vesicles and papules, some with central ulceration, were found in the superior and inferior eyelids. Mucoid discharge, chemosis, limbitis, and an anterior chamber reaction were also found. A conjunctival PCR swab for mpox was positive. The patient was treated with topical steroids with a good response. OCT and IVCM showed sub-endothelial deposits, stromal edema, hyperreflective multinucleated images in the epithelial layer, activated stromal images, and stromal edema characterized by fusiform hyperreflectivity that was resolved with the proposed treatment. This is the first report of OCT and IVCM in a non-immunosuppressed patient with mpox infection with a good response to topical steroids.
ISSN:0927-3948
1744-5078
1744-5078
DOI:10.1080/09273948.2023.2264388