Prevalence and clinical characteristics of uveitic glaucoma: multicentric study in Bogotá, Colombia

To describe the clinical features of patients diagnosed with uveitic glaucoma (UG) and ocular hypertension secondary to uveitis (OHT-SU). A multicentric cross-sectional study using medical records of patients with uveitis between 2013 and 2021. Uveitis and glaucoma specialists examined all patients....

Full description

Saved in:
Bibliographic Details
Published in:Eye (London) 2024-03, Vol.38 (4), p.714-722
Main Authors: Rojas-Carabali, William, Mejía-Salgado, Germán, Cifuentes-González, Carlos, Chacón-Zambrano, Daniela, Cruz-Reyes, Danna Lesley, Delgado, Maria Fernanda, Gómez-Goyeneche, Héctor Fernando, Saad-Brahim, Katrina, de-la-Torre, Alejandra
Format: Article
Language:English
Subjects:
Acuity
Adult
Child
Colombia - epidemiology
Complications
Cross-Sectional Studies
Female
Glaucoma
Glaucoma - epidemiology
Glaucoma - etiology
Glaucoma - therapy
Humans
Intraocular Pressure
Male
Medical records
Ocular Hypertension - diagnosis
Ocular Hypertension - epidemiology
Ocular Hypertension - etiology
Patients
Prevalence
Retrospective Studies
Survival analysis
Uveitis
Uveitis - diagnosis
Uveitis - drug therapy
Uveitis - epidemiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To describe the clinical features of patients diagnosed with uveitic glaucoma (UG) and ocular hypertension secondary to uveitis (OHT-SU). A multicentric cross-sectional study using medical records of patients with uveitis between 2013 and 2021. Uveitis and glaucoma specialists examined all patients. Variables were analyzed using the chi-square or Fisher's exact test for categorical variables. Additionally, t test, Mann-Whitney, and Kruskal-Wallis variance analysis were used for continuous variables. Finally, a Kaplan-Meier survival analysis for UG and OHT-SU development over time was done. Of the 660 clinical records reviewed of patients with uveitis, 191 (28.9%) had OHT-SU in at least one visit, and 108 (16.4%) of them developed UG. In all ages, females were more affected than males. Anterior uveitis was the main anatomic localisation, and non-granulomatous, recurrent, and inactive uveitis were the most frequent clinical features. The mean final visual acuity was 0.3 (0.0-1.0) LogMAR. Also, 95.8% of the patients had additional sequelae related to uveitis regardless of UG and OHT-SU. Interestingly, males had earlier affection, with statistical significance in OHT for adults (P = 0.036) and UG for children (P = 0.04). Of all patients, 81.1% received topical hypotensive treatment and 29.8% required a surgical procedure. UG and OHT-SU are common complications of uveitis in the Colombian population. These sight-threatening conditions were more common and appeared sooner in men at any age. Our results suggest that earlier and more aggressive treatment with topical hypotensive agents could positively influence the visual outcomes and the requirement of surgical procedures.
ISSN:0950-222X
1476-5454
DOI:10.1038/s41433-023-02757-9