Background free in vivo29Si MR imaging with hyperpolarized PEGylated silicon nanoparticles

This study demonstrated the potential of 50 nm PEGylated Si NPs for high-resolution in vivo29Si MR imaging, emphasizing their biocompatibility and water dispersibility. The acquisition of in vivo Si MR images using the lowest reported dose after subcutaneous and intraperitoneal administration opens...

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Bibliographic Details
Published in:Analyst (London) 2023-10, Vol.148 (21), p.5355-5360
Main Authors: Seung-Hyun, Yang, Kim, Jiwon, Lee, Tae Geol, Park, Mirae, Hye Young Son, Chan Gyu Joo, Shim, Jeong Hyun, Lee, Youngbok, Yong-Min, Huh
Format: Article
Language:English
Subjects:
Biocompatibility
Image acquisition
Image resolution
Magnetic resonance imaging
Nanoparticles
Silicon
Online Access:Get full text
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Description
Summary:This study demonstrated the potential of 50 nm PEGylated Si NPs for high-resolution in vivo29Si MR imaging, emphasizing their biocompatibility and water dispersibility. The acquisition of in vivo Si MR images using the lowest reported dose after subcutaneous and intraperitoneal administration opens new avenues for future 29Si MR studies.
ISSN:0003-2654
1364-5528
DOI:10.1039/d3an01395b