Exploring the effect of Ulva prolifera decay on the immune tissue of Paralichthys olivaceus based on transcriptomics and histopathological analysis

For 17 consecutive years, the outbreak of Ulva prolifera in the South Yellow Sea area of China has caused significant negative impacts on coastal ecological environment. However, its specific influence on fish immunity is rare. In this study, the juvenile Paralichthys olivaceus was exposed to fresh...

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Bibliographic Details
Published in:Marine pollution bulletin 2023-09, Vol.194, p.115410-115410, Article 115410
Main Authors: Shi, Kunpeng, Fan, Qingxin, Zhan, Min, Pang, Min, Tan, Suxu, Wang, Wenwen, Wang, Muyuan, Sha, Zhenxia
Format: Article
Language:English
Subjects:
Histopathological analysis
Paralichthys olivaceus
Transcriptome analysis
Ulva prolifera
Weighted correlation network analysis
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Summary:For 17 consecutive years, the outbreak of Ulva prolifera in the South Yellow Sea area of China has caused significant negative impacts on coastal ecological environment. However, its specific influence on fish immunity is rare. In this study, the juvenile Paralichthys olivaceus was exposed to fresh U. prolifera algae (FU) and decomposing algal effluent (DU). After short-term stress for 14 days, the histopathological and transcriptome analysis were performed to study the effect of U. prolifera decay on P. olivaceus. Histopathological analysis found that the liver, spleen and head kidneys of P. olivaceus were damaged after the short-term stress. The transcriptome results showed that the steroid biosynthesis signaling pathway and the PI3K-Akt signaling pathway were significantly enriched. Some immune related genes, including c1qc-like, dusp1, dusp16, HSP90 and metabolic related genes serotransferrin, were differentially expressed. These results highlighted the harmfulness of U. prolifera on marine fish, setting a solid foundation for further analyses. •Some immune and metabolic pathways of juvenile P. olivaceus was affected by the degradation of U. prolifera.•Weighted gene co-expression network analysis identified 63 core genes of P. olivaceus responding to U. prolifera.•The liver, spleen and head kidney of P. olivaceus were damaged with U. prolifera stress.
ISSN:0025-326X
1879-3363
DOI:10.1016/j.marpolbul.2023.115410