The Association of the UNOS Heart Allocation Policy Change With Transplant and Left Ventricular Assist Device Access and Outcomes

In October 2018, the allocation policy for adult orthotopic heart transplant (OHTx) in the United States was changed, with the goal of reducing waitlist mortality and providing broader sharing of donor organs within the United States. This study aimed to assess the association of this policy change...

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Bibliographic Details
Published in:The American journal of cardiology 2023-10, Vol.204, p.392-400
Main Authors: Fox, Daniel K., Waken, RJ, Wang, Fengxian, Wolfe, Jonathan D., Robbins, Keenan, Fanous, Erika, Vader, Justin M., Schilling, Joel D., Joynt Maddox, Karen E.
Format: Article
Language:English
Subjects:
Adult
Age
Extracorporeal membrane oxygenation
Gender
health policy
Heart Failure - surgery
Heart Transplantation
Heart transplants
Heart-Assist Devices
Hemodynamics
Hispanic people
Hospitalization
Hospitals
Humans
left ventricular assist devices (LVADs)
Medicaid
Medicare
Minority & ethnic groups
Morbidity
Mortality
orthotopic heart transplant (OHTx)
outcomes
Patients
Policy
Regression analysis
Regression models
Retrospective Studies
Subgroups
Trends
United States - epidemiology
Ventricle
Ventricular assist devices
Waiting Lists
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Summary:In October 2018, the allocation policy for adult orthotopic heart transplant (OHTx) in the United States was changed, with the goal of reducing waitlist mortality and providing broader sharing of donor organs within the United States. This study aimed to assess the association of this policy change with changes in access to OHTx versus left ventricular assist devices (LVADs), overall and in key sociodemographic subgroups, in the United States from 2016 to 2019. We identified all patients receiving OHTx or LVAD between 2016 and 2019 using the National Inpatient Sample. Controlling for medical co-morbidities, prepolicy trends, and within-hospital-year effects, we fit a dynamic logistic regression model to evaluate patient and hospital factors associated with receiving OHTx versus LVAD before versus after policy change. We also examined the frequency of temporary mechanical circulatory support in the same fashion. We identified 2,264 patients who received OHTx and 3,157 who received LVADs during the study period. In its first year of implementation, the United Network for Organ Sharing policy change of 2018 was associated with no overall change utilization of OHTx versus LVAD. In OHTx recipients, the frequency of use of temporary mechanical circulatory support changed from 15.6% in the before period to 42.6% in the after period (p 
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2023.07.090