Nasal Septal Perforation and Widespread Skin Lesions Caused by Mycobacterium chelonae Infection Mimicking Granulomatosis with Polyangiitis

Mycobacterium chelonae, a rapidly growing mycobacterium found in the natural environment, is known to cause localized lesions in the skin, soft tissue, and bone through traumatic inoculation, but widespread lesions are uncommon. We herein report an immunocompromised 79-year-old man suspected of havi...

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Bibliographic Details
Published in:Internal Medicine 2024/04/01, Vol.63(7), pp.1015-1019
Main Authors: Isogai, Shuntaro, Hayashi, Rion, Naniwa, Taio
Format: Article
Language:English
Subjects:
Aged
Bone diseases
Diagnosis, Differential
differential diagnosis
glucocorticoids
Granulomatosis
Granulomatosis with Polyangiitis - diagnosis
Humans
Immunocompromised hosts
Inoculation
Male
Mycobacterium chelonae
Mycobacterium Infections, Nontuberculous - diagnosis
Mycobacterium Infections, Nontuberculous - microbiology
Nasal Septal Perforation - diagnosis
Nasal Septal Perforation - etiology
nontuberculous mycobacterium infections, vasculitis
Skin diseases
Skin lesions
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Summary:Mycobacterium chelonae, a rapidly growing mycobacterium found in the natural environment, is known to cause localized lesions in the skin, soft tissue, and bone through traumatic inoculation, but widespread lesions are uncommon. We herein report an immunocompromised 79-year-old man suspected of having polyangiitis granulomatosis due to weight loss, epistaxis, and nasal crusts with impending septal perforation who was subsequently diagnosed with mucocutaneous and bone disease caused by widespread M. chelonae infection. Given these findings, clinicians should be aware of the tendency to develop unusual widespread lesions in immunocompromised patients, which can present a clinical picture similar to systemic vasculitides, such as granulomatosis with polyangiitis.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.2202-23