Rh(III)-Catalyzed Dienylation and Cyclopropylation of 1,2,3-Benzotriazinones with Alkylidenecyclopropanes

Rh (III)-catalyzed dienylation and cyclopropylation of 1,2,3-benzotriazinones with alkylidenecyclopropanes (ACPs) has been achieved. Different from the previous reports of 1,2,3-benzotriazinones, the triazinone ring remained intact in this C–H bond functionlization reaction. Also, the denitrogenativ...

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Bibliographic Details
Published in:Organic letters 2023-07, Vol.25 (28), p.5179-5184
Main Authors: Liu, Yan-Zhi, Zeng, Yao-Fu, Wei, Jiaohang, Xiao, Lin, Shu, Bing, Song, Jia-Lin, Zou, Wen-Xuan, Shen, Dan-Ting, Chen, Shao-Yong, Zheng, Yi-Chuan, Zhang, Shang-Shi
Format: Article
Language:English
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Summary:Rh (III)-catalyzed dienylation and cyclopropylation of 1,2,3-benzotriazinones with alkylidenecyclopropanes (ACPs) has been achieved. Different from the previous reports of 1,2,3-benzotriazinones, the triazinone ring remained intact in this C–H bond functionlization reaction. Also, the denitrogenative cyclopropylation could also be realized by changing the reaction temperature. This protocol is featured with high E selectivity, wide substrate scope, and divergent structures of products.
ISSN:1523-7060
1523-7052
DOI:10.1021/acs.orglett.3c01596