Risk factors associated with 10-year survival after coronary artery bypass grafting

Coronary artery bypass grafting (CABG) is the treatment of choice for a broad spectrum of patients with coronary disease. To describe global survival and factors associated with lower long-term survival in patients operated with isolated CABG. Analysis of a cohort of patients who underwent CABG betw...

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Published in:Revista medíca de Chile 2022-09, Vol.150 (9), p.1162-1170
Main Authors: González L, Roberto, Schaub C, Andrés, Alarcón O, Felipe, Reyes M, Rodrigo, Stockins L, Aleck, Seguel S, Enrique, Riquelme U, Alejandra, Barra M, Sebastián, Saldivia Z, Diego, Madrid C, Patricio, Pérez G, Alejandro, Alarcón C, Emilio
Format: Article
Language:Spanish
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Summary:Coronary artery bypass grafting (CABG) is the treatment of choice for a broad spectrum of patients with coronary disease. To describe global survival and factors associated with lower long-term survival in patients operated with isolated CABG. Analysis of a cohort of patients who underwent CABG between January 2006 and December 2008 at a public hospital. The database and operation records of 1.003 cardiac surgeries were reviewed. Of these, an isolated CABG was performed in 658 patients aged 62 ± 9 years including 516 male (78%). Survival data were obtained from the Chilean Civil Registry Office and a complete ten-year follow up was accomplished. Survival was analyzed with Kaplan-Meier method with log-rank test and Cox regression. Operative mortality occurred in 13 patients (2%). Survival at 1, 3, 5 and 10 years was 97, 94, 91 and 76%, respectively. One, 3, 5 and 10-year free of cardiovascular death survival was 98, 97, 95 y 89%, respectively. Factors associated with long-term survival were chronic kidney disease in hemodialysis (Hazard ratio (HR) 7.9; 95% confidence intervals (CI) 4.6-13.6), chronic obstructive pulmonary disease (HR 2.3; 95% CI 1.4-3.7), chronic arterial occlusive disease (HR 2.2; 95% CI 1.4-3.4) and diabetes mellitus (HR 1.9; 95% CI 1.4-2.6). According to EuroSCORE, 10-year survival was 86, 75 and 62% (p < 0.01) in low, medium and high-risk patients, respectively. These patients had a 10-year survival comparable to large international series. Groups associated with lower 10-year survival were identified.
ISSN:0717-6163
DOI:10.4067/S0034-98872022000901162