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Efficacy of ultraviolet B radiation versus vitamin D3 on postural control and cognitive functions in relapsing-remitting multiple sclerosis: A randomized controlled study
The relapsing-remitting multiple sclerosis (RRMS) is the most common type of MS with prevalence rate 20–60 patients/100.000 individuals in Egypt. Poor postural control and cognitive dysfunctions are well-established complications of RRMS without potent remedy yet. The latest evidence highlighted the...
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Published in: | Journal of bodywork and movement therapies 2023-07, Vol.35, p.49-56 |
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Main Authors: | , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites |
Online Access: | Get full text |
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Summary: | The relapsing-remitting multiple sclerosis (RRMS) is the most common type of MS with prevalence rate 20–60 patients/100.000 individuals in Egypt. Poor postural control and cognitive dysfunctions are well-established complications of RRMS without potent remedy yet. The latest evidence highlighted the potential and independent immune-modulating effects of vitamin D3 and ultraviolet radiation in the management of RRMS.
To investigate the efficacy of broadband ultraviolet B radiation (UVBR) versus moderate loading dose of vitamin D3 supplementation in improving postural control and cognitive functions.
Pretest-posttest randomized controlled study.
Multiple sclerosis outpatient unit of Kasr Al-Ainy Hospital.
Forty-seven patients with RRMS were recruited from both genders, yet only 40 completed the study.
Patients were randomized into two groups: UVBR group involved 24 patients, received sessions for 4 weeks and vitamin D3 group involved 23 patients, took vitamin D3 supplementation (50 000 IU/week) for 12 weeks.
Overall balance system index (OSI) and symbol digit modalities test (SDMT).
Highly significant decrease (P |
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ISSN: | 1360-8592 1532-9283 |
DOI: | 10.1016/j.jbmt.2023.04.069 |