Multi-modal imaging using a cascaded microscope design

We present a multi-modal fiber array snapshot technique (M-FAST) based on an array of 96 compact cameras placed behind a primary objective lens and a fiber bundle array. Our technique is capable of large-area, high-resolution, multi-channel video acquisition. The proposed design provides two key imp...

Full description

Saved in:
Bibliographic Details
Published in:Optics letters 2023-04, Vol.48 (7), p.1658-1661
Main Authors: Yang, Xi, Harfouche, Mark, Zhou, Kevin C, Kreiss, Lucas, Xu, Shiqi, Chandra Konda, Pavan, Kim, Kanghyun, Horstmeyer, Roarke
Format: Article
Language:English
Subjects:
Arrays
Cameras
Data acquisition
Image acquisition
Image contrast
Phase contrast
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We present a multi-modal fiber array snapshot technique (M-FAST) based on an array of 96 compact cameras placed behind a primary objective lens and a fiber bundle array. Our technique is capable of large-area, high-resolution, multi-channel video acquisition. The proposed design provides two key improvements to prior cascaded imaging system approaches: a novel optical arrangement that accommodates the use of planar camera arrays, and a new ability to acquire multi-modal image data acquisition. M-FAST is a multi-modal, scalable imaging system that can acquire snapshot dual-channel fluorescence images as well as differential phase contrast measurements over a large 6.59 mm × 9.74 mm field-of-view at 2.2- m center full-pitch resolution.
ISSN:0146-9592
1539-4794
DOI:10.1364/OL.471380