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Vulvar Complex Apocrine Carcinoma in a Horse (Equus caballus): A Case Report and Review of Literature
•Apocrine gland neoplasms are rarely reported neoplasms in equines.•The common location of tumor occurrence is the genitalia of animal•Simple neoplasms (proliferation of only epithelial cells) of the apocrine gland are reported in the equines. However, this is probably the first case report that des...
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Published in: | Journal of equine veterinary science 2023-08, Vol.127, p.104495-104495, Article 104495 |
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Main Authors: | , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites |
Online Access: | Get full text |
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Summary: | •Apocrine gland neoplasms are rarely reported neoplasms in equines.•The common location of tumor occurrence is the genitalia of animal•Simple neoplasms (proliferation of only epithelial cells) of the apocrine gland are reported in the equines. However, this is probably the first case report that describes the proliferation of epithelial and myoepithelial cells.•The myoepithelial components were confirmed by smooth muscle actin- alpha and p63.
A 6-year-old Marwari mare presented with recurrent vulvar growth. The growth was surgically excised, fixed and processed routinely. Microscopically, neoplasm showed proliferation of epithelial and myoepithelial cells with tubulopapillary pattern. On immunohistochemistry, myoepithelial cells showed strong immunoreactivity with smooth muscle actin alpha and p63. On basis of histopathology and immunohistochemistry, tumour was diagnosed as complex apocrine carcinoma. This case report describes first confirm vulvar complex apocrine carcinoma in equines. |
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ISSN: | 0737-0806 1542-7412 |
DOI: | 10.1016/j.jevs.2023.104495 |