Safety of topical medications in the management of paediatric atopic dermatitis: An updated systematic review

Aim New topical agents have been developed for the treatment of atopic dermatitis (AD) in recent years. This systematic review is intended to synthesize the clinical trial literature and concisely report the updated safety and adverse effects of topical medications used to treat atopic dermatitis in...

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Bibliographic Details
Published in:British journal of clinical pharmacology 2023-07, Vol.89 (7), p.2039-2065
Main Authors: Zhao, Sharon, Hwang, Austin, Miller, Corinne, Lio, Peter
Format: Article
Language:English
Subjects:
Adult
atopic dermatitis
calcineurin inhibitors
Calcineurin Inhibitors - adverse effects
Child
Child, Preschool
corticosteroids
Dermatitis, Atopic - drug therapy
Dermatologic Agents
Humans
Longitudinal Studies
Pruritus - chemically induced
Pruritus - drug therapy
safety
Tacrolimus
topical
Treatment Outcome
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Summary:Aim New topical agents have been developed for the treatment of atopic dermatitis (AD) in recent years. This systematic review is intended to synthesize the clinical trial literature and concisely report the updated safety and adverse effects of topical medications used to treat atopic dermatitis in children. Methods A systematic search of Cochrane Library, Embase, PubMed and ClinicalTrials.gov from inception to March 2022 was conducted for trials of topical medications used to treat AD in patients
ISSN:0306-5251
1365-2125
DOI:10.1111/bcp.15751