Prospective validation of diffusion-weighted MRI as a biomarker of tumor response and oncologic outcomes in head and neck cancer: Results from an observational biomarker pre-qualification study

•Patients with CR had a significant increase in ADCmean at mid-RT.•Primary tumor ΔADCmean 

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Bibliographic Details
Published in:Radiotherapy and oncology 2023-06, Vol.183, p.109641-109641, Article 109641
Main Authors: Mohamed, Abdallah S.R., Abusaif, Abdelrahman, He, Renjie, Wahid, Kareem A., Salama, Vivian, Youssef, Sara, McDonald, Brigid A., Naser, Mohamed, Ding, Yao, Salzillo, Travis C., AboBakr, Moamen A., Wang, Jihong, Lai, Stephen Y., Fuller, Clifton D.
Format: Article
Language:English
Subjects:
Biomarkers
Diffusion Magnetic Resonance Imaging - methods
DWI
Head and neck cancer
Head and Neck Neoplasms - diagnostic imaging
Head and Neck Neoplasms - radiotherapy
Humans
Imaging Biomarker
Magnetic Resonance Imaging
Neoplasm Recurrence, Local - diagnostic imaging
Oncologic outcomes
Prospective Studies
Radiation Therapy
Tumor response
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Description
Summary:•Patients with CR had a significant increase in ADCmean at mid-RT.•Primary tumor ΔADCmean 
ISSN:0167-8140
1879-0887
DOI:10.1016/j.radonc.2023.109641