Uterine artery Doppler in early labor and perinatal outcome in low‐risk term pregnancy: prospective multicenter study

ABSTRACT Objective The prediction of adverse perinatal outcomes in low‐risk pregnancies is poor, mainly owing to the lack of reliable biomarkers. Uterine artery (UtA) Doppler is closely associated with placental function and may facilitate the peripartum detection of subclinical placental insufficie...

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Bibliographic Details
Published in:Ultrasound in obstetrics & gynecology 2023-08, Vol.62 (2), p.219-225
Main Authors: Dall'asta, A., Figueras, F., Rizzo, G., Ramirez Zegarra, R., Morganelli, G., Giannone, M., Cancemi, A., Mappa, I., Lees, C., Frusca, T., Ghi, T.
Format: Article
Language:English
Subjects:
adverse perinatal outcome
Apgar score
Biomarkers
Birth weight
Cesarean Section
Childbirth & labor
emergency Cesarean section
Female
fetal distress
Fetuses
Gynecology
Humans
Infant, Newborn
Intervention
intrapartum fetal compromise
Labor
Likelihood ratio
Neonates
Observational studies
obstetric risk
Obstetrics
operative delivery
Placenta
Placenta - blood supply
placental insufficiency
Pregnancy
Pregnancy Outcome - epidemiology
Pregnancy Trimester, Third
Prospective Studies
Pulsatile Flow
Regression analysis
Risk
Ultrasonic imaging
Ultrasonography, Doppler
Ultrasonography, Prenatal
Ultrasound
Umbilical Arteries - diagnostic imaging
Uterine Artery - diagnostic imaging
Uterus
Veins & arteries
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Summary:ABSTRACT Objective The prediction of adverse perinatal outcomes in low‐risk pregnancies is poor, mainly owing to the lack of reliable biomarkers. Uterine artery (UtA) Doppler is closely associated with placental function and may facilitate the peripartum detection of subclinical placental insufficiency. The objective of this study was to evaluate the association of mean UtA pulsatility index (PI) measured in early labor with obstetric intervention for suspected intrapartum fetal compromise and adverse perinatal outcome in uncomplicated singleton term pregnancies. Methods This was a prospective multicenter observational study conducted across four tertiary maternity units. Low‐risk term pregnancies with spontaneous onset of labor were included. The mean UtA‐PI was recorded between uterine contractions in women admitted for early labor and converted into multiples of the median (MoM). The primary outcome of the study was the occurrence of obstetric intervention, i.e. Cesarean section or instrumental delivery, for suspected intrapartum fetal compromise. Secondary outcomes were the occurrence of adverse perinatal outcomes, including 5‐min Apgar score
ISSN:0960-7692
1469-0705
DOI:10.1002/uog.26199