Resolution of Liver Function Tests After Laparoscopic Common Bile Duct Exploration Versus Endoscopic Retrograde Cholangiopancreatography

Laparoscopic cholecystectomy (LC) with laparoscopic common bile duct exploration (LCBDE) is gaining traction for the management of choledocholithiasis. Liver function tests (LFTs) are often used to determine the success of ductal clearance, yet the impact of differing therapeutic interventions, endo...

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Bibliographic Details
Published in:The American surgeon 2023-07, Vol.89 (7), p.3171-3173
Main Authors: Cambronero, Gabriel E., Sanin, Gloria D., Patterson, James W., Ganapathy, Aravindh S., Bosley, Maggie E., Niebler, Jake, Perko, Allison, Westcott, Carl, Nunn, Andrew M., Neff, Lucas P.
Format: Article
Language:English
Subjects:
Bilirubin
Cholangiopancreatography, Endoscopic Retrograde - methods
Cholecystectomy, Laparoscopic - adverse effects
Cholecystectomy, Laparoscopic - methods
Choledocholithiasis - surgery
Common Bile Duct - surgery
Humans
Liver Function Tests
Retrospective Studies
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Summary:Laparoscopic cholecystectomy (LC) with laparoscopic common bile duct exploration (LCBDE) is gaining traction for the management of choledocholithiasis. Liver function tests (LFTs) are often used to determine the success of ductal clearance, yet the impact of differing therapeutic interventions, endoscopic retrograde cholangiopancreatography (ERCP) or LCBDE, have on postprocedure LFT is insufficiently described. We hypothesize that these interventions have different postoperative LFT profiles. The preprocedural and postprocedural total bilirubin (Tbili), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) were analyzed of 167 patients who had successful ERCPs (117) or LCBDEs (50). Endoscopic retrograde cholangiopancreatography patients demonstrated a significant decrease in all LFTs postprocedure (n = 117; P =
ISSN:0003-1348
1555-9823
DOI:10.1177/00031348231161688