Novel concepts in the pathogenesis of hydrocephalus

Purpose Hydrocephalus is a multifactorial neurological disorder and one of the most common neurosurgical conditions characterized by excessive cerebrospinal fluid (CSF) accumulation within the brain’s ventricles. It can result in dilatation of the ventricular system caused by the inadequate passage...

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Bibliographic Details
Published in:Child's nervous system 2023-05, Vol.39 (5), p.1245-1252
Main Authors: Figueiredo, Marcos V. D’Amato, Alexiou, George, Laube, Kaito A. Carvalho, Manfroi, Gregori, Rehder, Roberta
Format: Article
Language:English
Subjects:
Cerebral Ventricles - pathology
Cerebrospinal Fluid
Humans
Hydrocephalus - surgery
Medicine
Medicine & Public Health
Neurosciences
Neurosurgery
Quality of Life
Review
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Summary:Purpose Hydrocephalus is a multifactorial neurological disorder and one of the most common neurosurgical conditions characterized by excessive cerebrospinal fluid (CSF) accumulation within the brain’s ventricles. It can result in dilatation of the ventricular system caused by the inadequate passage of CSF from its point of production within the ventricles to its point of absorption into the systemic circulation. Recent findings on the genetics and molecular studies of hydrocephalus have the potential to improve treatment and quality of life. Methods Review of literature on the novel studies of the pathogenesis of hydrocephalus. Conclusion Molecular studies on the pathogenesis of hydrocephalus have provided a means to improve the treatment and follow-up of patients with hydrocephalus.
ISSN:0256-7040
1433-0350
DOI:10.1007/s00381-023-05891-7