Is There a Role for Imaging Youth at Risk of Atherosclerosis?

Purpose of Review Cardiovascular (CV) risk factors such as dyslipidemia, hypertension, diabetes, and obesity are associated with an increased risk for CV events in adults. Noninvasive measures of vascular health are associated with these CV events and can potentially help risk stratify children with...

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Bibliographic Details
Published in:Current atherosclerosis reports 2023-04, Vol.25 (4), p.119-126
Main Authors: Tran, Andrew H., Urbina, Elaine M.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Angiology
Atherosclerosis - diagnostic imaging
Cardiology
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - etiology
Carotid Intima-Media Thickness
Child
Humans
Medicine
Medicine & Public Health
Pulse Wave Analysis - methods
Risk Assessment - methods
Risk Factors
Topical Collection on Children/Adolescents/Young Adults and Atherosclerosis
Vascular Stiffness
Citations: Items that this one cites
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Summary:Purpose of Review Cardiovascular (CV) risk factors such as dyslipidemia, hypertension, diabetes, and obesity are associated with an increased risk for CV events in adults. Noninvasive measures of vascular health are associated with these CV events and can potentially help risk stratify children with CV risk factors. The purpose of this review is to summarize recent literature regarding vascular health in children with cardiovascular risk factors. Recent Findings Adverse changes in pulse wave velocity, pulse wave analysis, arterial distensibility, and carotid intima-media thickness are seen in children with CV risk factors supporting potential utility in risk stratification. Assessing vascular health in children can be challenging due to growth-related changes in vasculature, multiple assessment modalities, and differences in normative data. Summary Vascular health assessment in children with cardiovascular risk factors can be a valuable tool for risk stratification and help identify opportunities for early intervention. Future areas of research include increasing normative data, improving conversion of data between different modalities, and increasing longitudinal studies in children linking childhood risk factors to adult CV outcomes.
ISSN:1523-3804
1534-6242
DOI:10.1007/s11883-023-01089-z