Reducing MRSA Infection in a New NICU During the COVID-19 Pandemic

Methicillin-resistant Staphylococcus aureus (MRSA) is prevalent in most NICUs, with a high rate of skin colonization and subsequent invasive infections among hospitalized neonates. The effectiveness of interventions designed to reduce MRSA infection in the NICU during the coronavirus disease 2019 (C...

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Bibliographic Details
Published in:Pediatrics (Evanston) 2023-02, Vol.151 (2), p.1
Main Authors: Barrett, Renee E, Fleiss, Noa, Hansen, Caitlin, Campbell, Melissa M, Rychalsky, Michelle, Murdzek, Christina, Krechevsky, Kathy, Abbott, Meaghan, Allegra, Terese, Blazevich, Beth, Dunphy, Louise, Fox, Amy, Gambardella, Tracy, Garcia, Lindsey, Grimm, Natalie, Scoffone, Amy, Bizzarro, Matthew J, Murray, Thomas S
Format: Article
Language:English
Subjects:
COVID-19
COVID-19 - prevention & control
Cross Infection - epidemiology
Cross Infection - prevention & control
Drug resistance
Humans
Infant, Newborn
Infection Control
Intensive care
Intensive Care Units, Neonatal
Methicillin-Resistant Staphylococcus aureus
Neonatal care
Pandemics - prevention & control
Pediatrics
Staphylococcal Infections - epidemiology
Staphylococcal Infections - prevention & control
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Summary:Methicillin-resistant Staphylococcus aureus (MRSA) is prevalent in most NICUs, with a high rate of skin colonization and subsequent invasive infections among hospitalized neonates. The effectiveness of interventions designed to reduce MRSA infection in the NICU during the coronavirus disease 2019 (COVID-19) pandemic has not been characterized. Using the Institute for Healthcare Improvement's Model for Improvement, we implemented several process-based infection prevention strategies to reduce invasive MRSA infections at our level IV NICU over 24 months. The outcome measure of invasive MRSA infections was tracked monthly utilizing control charts. Process measures focused on environmental disinfection and hospital personnel hygiene were also tracked monthly. The COVID-19 pandemic was an unexpected variable during the implementation of our project. The pandemic led to restricted visitation and heightened staff awareness of the importance of hand hygiene and proper use of personal protective equipment, as well as supply chain shortages, which may have influenced our outcome measure. Invasive MRSA infections were reduced from 0.131 to 0 per 1000 patient days during the initiative. This positive shift was sustained for 30 months, along with a delayed decrease in MRSA colonization rates. Several policy and practice changes regarding personnel hygiene and environmental cleaning likely contributed to this reduction. Implementation of a multidisciplinary quality improvement initiative aimed at infection prevention strategies led to a significant decrease in invasive MRSA infections in the setting of the COVID-19 pandemic.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.2022-057033