Incidence of Sinus Inflammation After Endoscopic Skull Base Surgery in the Pediatric Population

Background The extended endonasal approach has been utilized in the resection of anterior skull base lesions in the pediatric population. There are unique challenges to these patients in the post‐operative setting, including patient compliance with medical therapy and post‐operative debridements, an...

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Bibliographic Details
Published in:The Laryngoscope 2023-08, Vol.133 (8), p.2014-2017
Main Authors: Henry, Laura E., Eide, Jacob G., Kshirsagar, Rijul S., Tong, Charles C. L., Kuan, Edward C., Poonia, Seerat K., Storm, Phillip B., Palmer, James N., Adappa, Nithin D.
Format: Article
Language:English
Subjects:
Child
craniopharyngioma
endoscopic surgery
Endoscopy
Endoscopy - adverse effects
Female
Humans
Incidence
Inflammation
Inflammation - epidemiology
Inflammation - etiology
Laryngoscopy
Male
Nose - surgery
Patients
pediatric tumor
Pediatrics
Retrospective Studies
Rhinitis
rhinosinusitis
Sinusitis
Sinusitis - surgery
skull base
Skull Base - diagnostic imaging
Skull Base - surgery
Surgery
trans‐sphenoidal surgery
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Summary:Background The extended endonasal approach has been utilized in the resection of anterior skull base lesions in the pediatric population. There are unique challenges to these patients in the post‐operative setting, including patient compliance with medical therapy and post‐operative debridements, and a smaller nasal airway that may increase propensity toward scarring. Our objective for this study is to evaluate the incidence of post‐operative radiographic inflammation in this patient population using the Lund‐Mackay (LM) score. Methods A single‐center, retrospective review of pediatric patients undergoing endoscopic approach to the skull base between 2009 and 2021 was performed. Demographic and clinicopathologic data and pre‐ and post‐operative imaging were analyzed. One‐way ANOVA followed by Tukey multiple pairwise comparisons statistical tests were used to compare mean LM scores between groups. Results Seventy‐two patients (52 males, 20 females) were identified with a median follow‐up of 27 months. All patients underwent an extended endonasal approach for resection of skull base lesions. The mean LM scores were compared between pre‐operative MRI, first post‐operative MRI > 30 days after surgery, and most recent post‐operative MRI. One‐way ANOVA was performed with significant differences noted between the groups (p 
ISSN:0023-852X
1531-4995
DOI:10.1002/lary.30415