Percutaneous Large-Bore Pulmonary Thrombectomy with the FlowTriever Device: Initial Experience in Intermediate-High and High-Risk Patients

Objectives This retrospective cohort study investigates outcomes of patients with intermediate-high and high-risk pulmonary embolism (PE) who were treated with transfemoral mechanical thrombectomy (MT) using the large-bore Inari FlowTriever aspiration catheter system. Material and Methods Twenty-sev...

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Bibliographic Details
Published in:Cardiovascular and interventional radiology 2023, Vol.46 (1), p.35-42
Main Authors: Luedemann, W. M., Zickler, D., Kruse, J., Koerner, R., Lenk, J., Erxleben, C., Torsello, G. F., Fehrenbach, U., Jonczyk, M., Guenther, R. W., De Bucourt, M., Gebauer, B.
Format: Article
Language:English
Subjects:
Adult
Aged
Arterial Interventions
Cardiology
Clinical Investigation
Complications
Embolism
Embolisms
Heart
Heart rate
Hemodynamics
Humans
Imaging
Medical instruments
Medicine
Medicine & Public Health
Middle Aged
Nuclear Medicine
Patients
Population studies
Pulmonary arteries
Pulmonary artery
Pulmonary Embolism - diagnostic imaging
Pulmonary Embolism - etiology
Pulmonary Embolism - therapy
Pulmonary embolisms
Radiology
Retrospective Studies
Risk
Risk groups
Statistical analysis
Thrombectomy - methods
Thrombolysis
Thrombolytic Therapy - methods
Thrombosis - etiology
Treatment Outcome
Ultrasound
Ventricle
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Summary:Objectives This retrospective cohort study investigates outcomes of patients with intermediate-high and high-risk pulmonary embolism (PE) who were treated with transfemoral mechanical thrombectomy (MT) using the large-bore Inari FlowTriever aspiration catheter system. Material and Methods Twenty-seven patients (mean age 56.1 ± 15.3 years) treated with MT for PE between 04/2021 and 11/2021 were reviewed. Risk stratification was performed according to European Society of Cardiology (ESC) guidelines. Clinical and hemodynamic characteristics before and after the procedure were compared with the paired Student’s t test, and duration of hospital stay was analyzed with the Kaplan–Meier estimator. Procedure-related adverse advents were assessed. Results Of 27 patients treated, 18 were classified as high risk. Mean right-to-left ventricular ratio on baseline CT was 1.7 ± 0.6. After MT, a statistically significant reduction in mean pulmonary artery pressures from 35.9 ± 9.6 to 26.1 ± 9.0 mmHg ( p  = 0.002) and heart rates from 109.4 ± 22.5 to 82.8 ± 13.8 beats per minute ( p  
ISSN:0174-1551
1432-086X
DOI:10.1007/s00270-022-03266-0