Treatment of Nontuberculous Mycobacterial (NTM) Pulmonary Infection in the US Bronchiectasis and NTM Registry: Treatment Patterns, Adverse Events, and Adherence to American Thoracic Society/Infectious Disease Society of America Treatment Guidelines

Among 1038 participants with pulmonary Mycobacterium avium complex and 120 with Mycobacterium abscessus enrolled in the US Bronchiectasis and NTM Research Registry, less than half received antibiotic therapy in the 24 months before registry enrollment, of which less than half were guideline based. A...

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Bibliographic Details
Published in:Clinical infectious diseases 2023-01, Vol.76 (2), p.338-341
Main Authors: Ku, Jennifer H, Henkle, Emily, Aksamit, Timothy R, Barker, Alan, Brunton, Amanda E, Winthrop, Kevin L
Format: Article
Language:English
Subjects:
Bronchiectasis - drug therapy
Communicable Diseases
Humans
Lung - microbiology
Lung Diseases - microbiology
Mycobacterium avium Complex
Mycobacterium Infections, Nontuberculous - drug therapy
Mycobacterium Infections, Nontuberculous - epidemiology
Mycobacterium Infections, Nontuberculous - microbiology
Nontuberculous Mycobacteria
Opportunistic Infections
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Summary:Among 1038 participants with pulmonary Mycobacterium avium complex and 120 with Mycobacterium abscessus enrolled in the US Bronchiectasis and NTM Research Registry, less than half received antibiotic therapy in the 24 months before registry enrollment, of which less than half were guideline based. Adverse effects occurred in 21% of therapy recipients, of whom 33% discontinued therapy.
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciac788