Acupuncture for Uremic Pruritus: A Systematic Review and Meta-Analysis

Uremic pruritus (UP) is a chronic disease that can seriously affect the quality of life of dialysis patients. Acupuncture is a non-medication therapy that has been used to treat pruritus disorders. This systematic review aimed to evaluate the efficacy and safety of acupuncture for the treatment of U...

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Bibliographic Details
Published in:Journal of pain and symptom management 2023-01, Vol.65 (1), p.e51-e62
Main Authors: Zhang, Leixiao, Li, Yiwei, Xiao, Xianjun, Shi, Yunzhou, Xu, Dongxian, Li, Ning, Deng, Yanli
Format: Article
Language:English
Subjects:
acupuncture
Acupuncture Therapy - adverse effects
Acupuncture Therapy - methods
hemodialysis
Humans
meta-analysis
Pruritus - etiology
Pruritus - therapy
Quality of Life
Renal Dialysis
systematic review
Uremic pruritus
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Summary:Uremic pruritus (UP) is a chronic disease that can seriously affect the quality of life of dialysis patients. Acupuncture is a non-medication therapy that has been used to treat pruritus disorders. This systematic review aimed to evaluate the efficacy and safety of acupuncture for the treatment of UP. A total of nine Chinese and English databases were searched from their inception to December 31, 2021, and 214 studies were retrieved. Finally, seven randomized controlled trials (n=504) were included in the meta-analysis performed using RevMan V.5.3. Results included effective rate, recurrence rates, and adverse events. Compared with conventional treatment, acupuncture was more effective in treating UP (risk ratio [RR]=1.28, 95% confidence interval [CI]=1.09 to 1.50, P=0.003). The results were consistent after sensitivity analysis (RR=1.38, 95% CI=1.21 to 1.57, P
ISSN:0885-3924
1873-6513
DOI:10.1016/j.jpainsymman.2022.08.017