Sonographic evaluation of subclinical entheseal involvement in patients with hypoparathyroidism: a case control study

Purpose Hypoparathyroidism is a disease characterized by low serum calcium, increased serum phosphorus and low PTH levels. Although patients are treated with active vitamin D and calcium, a proper serum calcium phosphorus balance cannot always be achieved. Ectopic calcifications that develop in orga...

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Bibliographic Details
Published in:Journal of endocrinological investigation 2023-01, Vol.46 (1), p.133-139
Main Authors: Fırat, S. N., Kuşkonmaz, Ş. M., Önder, Ç. E., Omma, T., Genç, H., Çulha, C.
Format: Article
Language:English
Subjects:
Calcium
Calcium (blood)
Case-Control Studies
Correlation analysis
Endocrinology
Enthesopathy
Humans
Hypoparathyroidism
Hypoparathyroidism - diagnostic imaging
Hypoparathyroidism - etiology
Hypothyroidism
Internal Medicine
Medicine
Medicine & Public Health
Metabolic Diseases
Original Article
Parathyroid Hormone
Phosphorus
Statistical analysis
Ultrasonic imaging
Ultrasound
Vitamin D
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Summary:Purpose Hypoparathyroidism is a disease characterized by low serum calcium, increased serum phosphorus and low PTH levels. Although patients are treated with active vitamin D and calcium, a proper serum calcium phosphorus balance cannot always be achieved. Ectopic calcifications that develop in organs during treatment are the most common complications. To date, there is not any published study on enthesopathy in patients with hypoparathyroidism. The aim of this study was to evaluate subclinical enthesopathy in patients with hypoparathyroidism with ultrasound and to compare the results with those of the control group. Methods The study included patients aged 18–65 years with postoperative hypoparathyroidism and hypothyroidism (group hypoP + hypoT), patients with postoperative hypothyroidism (group hypoT), and healthy age and sex-matched volunteers (group C). Ultrasonographic findings of enthesopathy in both extremities were documented according to the Glasgow Ultrasound Enthesitis Scoring System (GUESS). Results GUESS scores in group hypoP + hypoT, were significantly higher when compared to the other groups. There was a statistically significant correlation between the total GUESS scores and total enthesophyte scores and the duration of hypoparathyroidism ( p  
ISSN:1720-8386
0391-4097
1720-8386
DOI:10.1007/s40618-022-01891-7