Predictors of Oculomotor Nerve Palsy with Posterior Communicating Aneurysm Clipping in a Surgically Treated Series of 585 Patients: A Single-Center Study

Oculomotor nerve palsy (OMNP) is a known risk in surgical management of intracranial aneurysms. The aim of this study was to determine the risk factors for surgery-induced OMNP. This retrospective study examined 585 patients with posterior communicating artery aneurysms treated surgically between Ja...

Full description

Saved in:
Bibliographic Details
Published in:World neurosurgery 2022-11, Vol.167, p.e117-e121
Main Authors: Liu, Heng-Jian, Lin, Yuan, Feng, Yu-Gong
Format: Article
Language:English
Subjects:
Clipping
Factors
Humans
Intracranial Aneurysm - complications
Intracranial Aneurysm - surgery
Oculomotor Nerve Diseases - epidemiology
Oculomotor Nerve Diseases - etiology
Oculomotor Nerve Diseases - surgery
Oculomotor nerve palsy
Posterior communicating artery aneurysm
Projection
Retrospective Studies
Risk Factors
Subarachnoid Hemorrhage - complications
Subarachnoid Hemorrhage - surgery
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Oculomotor nerve palsy (OMNP) is a known risk in surgical management of intracranial aneurysms. The aim of this study was to determine the risk factors for surgery-induced OMNP. This retrospective study examined 585 patients with posterior communicating artery aneurysms treated surgically between January 2000 and July 2019. The patients were categorized into 2 groups according to whether they experienced OMNP. Multiple factors, including sex, age, history of subarachnoid hemorrhage, Hunt and Hess grade, Fisher grade, preoperative time, sizes, sides, number, orientation, intraoperative rupture, and morphology, were analyzed to identify factors associated with surgery-induced OMNP. The overall OMNP rate was 4.4%. In univariate analysis, large size (P < 0.001), posterior infratentorial projection (P = 0.003), number of subarachnoid hemorrhages (P = 0.005), and late preoperative time (P < 0.001) were associated with increased risk of OMNP. Overall, multivariate logistic regression analysis showed that size (10.1–25 mm: odds ratio [OR] 30.083, P = 0.001, 95% confidence interval [CI], 3.703–244.419; >25 mm: OR 62.179, P = 0.012, 95% CI, 2.402–1609.418), intraoperative rupture (OR 3.018, P = 0.035, 95% CI, 1.083–8.412), and preoperative time (>14 days: OR 10.985, P < 0.001, 95% CI, 3.840–31.428) were independent risk factors of surgery-induced OMNP. This study showed that size, intraoperative rupture, and preoperative time were independent predictors of surgery-induced OMNP. Use of advanced technologies during the operation can assist in avoiding this complication.
ISSN:1878-8750
1878-8769
1878-8769
DOI:10.1016/j.wneu.2022.07.101