A longitudinal study of unilateral Ménière's disease and clinical evolutionary models

The heterogeneity of Ménière's disease is presently defined by a variety of subtypes. This study introduced three different subtypes of unilateral Ménière's disease based on the evolution of vertigo crises from their inception. A longitudinal descriptive study of 327 unilateral Ménière...

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Bibliographic Details
Published in:Journal of laryngology and otology 2023-06, Vol.137 (6), p.629-636
Main Authors: Pérez-Carbonell, T, Orts-Alborch, M, Pérez-Guillén, V, Tenías-Burillo, J M, Pla-Gil, I, Marco-Algarra, J, Pérez-Garrigues, H
Format: Article
Language:English
Subjects:
Confidence intervals
Disease
Evolution
Hearing loss
Longitudinal studies
Main Article
Meniere's disease
Otolaryngology
Patients
Remission (Medicine)
Statistical analysis
Surgery
Variables
Vertigo
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Summary:The heterogeneity of Ménière's disease is presently defined by a variety of subtypes. This study introduced three different subtypes of unilateral Ménière's disease based on the evolution of vertigo crises from their inception. A longitudinal descriptive study of 327 unilateral Ménière's disease patients was performed. In a subgroup of patients followed from the onset of the disease, 3 subtypes of unilateral Ménière's disease were defined according to the vertiginous crises suffered during the first 10 years of the disorder. Data was available for 87 patients with unilateral Ménière's disease from the start of their disease (26.6 per cent of the original sample). These patients were grouped into three models according to their symptomatic evolution. Model 3 was associated with a worse hearing prognosis, a greater number of Tumarkin's otolithic crises and the need for surgery. Model 1 presented less hearing loss. Unilateral Ménière's disease models based on the evolution of vertiginous crises present differences according to aspects such as hearing loss, vertiginous crisis, Tumarkin's otolithic crisis and the need for surgery.
ISSN:0022-2151
1748-5460
DOI:10.1017/S0022215122001773