Effect of Novel Stratified Lipid Risk by “LDL-Window” and Flow-Mediated Dilation on the Prognosis of Coronary Artery Disease Using the FMD-J Study A Data

Background: Elevated levels of triglyceride (TG) and non-high-density lipoprotein cholesterol (non-HDL-C) are regarded as a residual lipid risk in low-density lipoprotein cholesterol (LDL-C)-lowering therapy. This study investigated the association between lipid risk stratified by TG and non-HDL-C a...

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Published in:Circulation Journal 2022/08/25, Vol.86(9), pp.1444-1454
Main Authors: Abe, Shichiro, Haruyama, Yasuo, Kobashi, Gen, Toyoda, Shigeru, Inoue, Teruo, Tomiyama, Hirofumi, Ishizu, Tomoko, Kohro, Takahide, Higashi, Yukihito, Takase, Bonpei, Suzuki, Toru, Ueda, Shinichiro, Yamazaki, Tsutomu, Furumoto, Tomoo, Kario, Kazuomi, Koba, Shinji, Takemoto, Yasuhiko, Hano, Takuzo, Sata, Masataka, Ishibashi, Yutaka, Node, Koichi, Maemura, Koji, Ohya, Yusuke, Furukawa, Taiji, Ito, Hiroshi, Yamashina, Akira
Format: Article
Language:English
Subjects:
Coronary artery disease
Flow-mediated dilation
Lipid risk stratification
Non-high-density lipoprotein cholesterol
Triglyceride
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Summary:Background: Elevated levels of triglyceride (TG) and non-high-density lipoprotein cholesterol (non-HDL-C) are regarded as a residual lipid risk in low-density lipoprotein cholesterol (LDL-C)-lowering therapy. This study investigated the association between lipid risk stratified by TG and non-HDL-C and the prognosis of patients with coronary artery disease (CAD), and the association between stratified lipid risk and flow-mediated dilatation (FMD) index.Methods and Results: The 624 CAD patients enrolled in flow-mediated dilation (FMD)-J study A were divided into 4 groups: low-risk group (n=413) with TG
ISSN:1346-9843
1347-4820
1347-4820
DOI:10.1253/circj.CJ-21-1068