Pretreatment [18F]FDG PET/CT and MRI in the prognosis of nasopharyngeal carcinoma
Objective The present study aimed to assess the prognostic interest of metabolic and anatomic parameters derived from 2-deoxy-2-[ 18 F]fluoro- d -glucose positron emission tomography/computed tomography ([ 18 F]FDG PET/CT) and head and neck magnetic resonance imaging (HN-MRI) for better management o...
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Published in: | Annals of nuclear medicine 2022-10, Vol.36 (10), p.876-886 |
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Main Authors: | , , , , , , , , , , |
Format: | Article |
Language: | eng |
Subjects: | |
Online Access: | Get full text |
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Summary: | Objective
The present study aimed to assess the prognostic interest of metabolic and anatomic parameters derived from 2-deoxy-2-[
18
F]fluoro-
d
-glucose positron emission tomography/computed tomography ([
18
F]FDG PET/CT) and head and neck magnetic resonance imaging (HN-MRI) for better management of nasopharyngeal carcinoma (NPC).
Methods
In this study, pre-treatment [
18
F]FDG PET/CT and HN-MRI parameters of NPC patients diagnosed between January 2017 and December 2018, were prospectively investigated. Correlation between those parameters and 4-year patient’s survival outcomes was evaluated using Kaplan–Meier and Cox-regression analyses.
Results
Our results revealed a significant association between pre-treatment nodal-maximum standardized uptake value (N-SUV max) and N categories (
p
= 0.01), between pre-treatment node-to-tumor SUV ratio (NTR) and both tumor size (
p
= 0.01) and N categories (
p
= 0.009), as well as between metabolic tumor volume (MTV) and both tumor size and NPC overall stage (
p
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ISSN: | 0914-7187 1864-6433 |