Two‐ versus three‐field lymphadenectomy for esophageal cancer. A systematic review and meta‐analysis of early and late results

This study aims to estimate whether prophylactic cervical lymphadenectomy for esophageal cancer influences the short‐ and long‐term results through a systematic literature review and meta‐analysis. Twenty‐eight articles were selected in this systematic review, encompassing 9180 patients. Prophylacti...

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Bibliographic Details
Published in:Journal of surgical oncology 2022-07, Vol.126 (1), p.76-89
Main Authors: Datrino, Letícia Nogueira, Orlandini, Marina Feliciano, Serafim, Maria Carolina Andrade, dos Santos, Clara Lucato, Modesto, Victoria Andrade, Tavares, Guilherme, Tristão, Luca Schiliró, Bernardo, Wanderley M., Tustumi, Francisco
Format: Article
Language:English
Subjects:
Cancer surgery
Esophageal cancer
esophagus
lymphadenectomy
Lymphatic system
Meta-analysis
Systematic review
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Summary:This study aims to estimate whether prophylactic cervical lymphadenectomy for esophageal cancer influences the short‐ and long‐term results through a systematic literature review and meta‐analysis. Twenty‐eight articles were selected in this systematic review, encompassing 9180 patients. Prophylactic neck lymphadenectomy for esophageal cancer should be performed with caution, as it is associated with worse short‐term results compared to traditional two‐field lymphadenectomy and does not improve long‐term survival.
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.26857