Acute mushroom poisoning of Amanita pseudosychnopyramis: A case report from Fujian, China with exact species identification and descriptive study

Mushroom poisoning is a deeply concerning food safety problem that affects the public in China every year. Although there are statistics on the number of poisonings and incidents, there is a lack of data on the types of toxic mushrooms, clinical manifestations and toxins. A case of wild mushroom poi...

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Bibliographic Details
Published in:Toxicon (Oxford) 2022-06, Vol.212, p.55-61
Main Authors: Chen, Jing-Ze, Fu, Wu-Sheng, Xu, Fei, Fang, Qin-Mei, Zheng, Kui-Cheng, Lin, Zhong, Lin, Yi-Ming, Zhang, Sophia
Format: Article
Language:English
Subjects:
Descriptive epidemiological investigation
Ibotenic acid
Muscarine
Muscimol
Mushroom poisoning
Species identification
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Summary:Mushroom poisoning is a deeply concerning food safety problem that affects the public in China every year. Although there are statistics on the number of poisonings and incidents, there is a lack of data on the types of toxic mushrooms, clinical manifestations and toxins. A case of wild mushroom poisoning occurred in Xiamen. Descriptive epidemiological investigation, toxins detection, and morphological and phylogenetic identification were immediately performed. The patients exhibited typical neurotoxic symptoms after consuming wild mushrooms, including chills, vertigo, drowsiness, salivation and coma. The average incubation period was 30 min. Treatments that were adopted included fluid infusion, gastric lavage, catharsis, and liver protection treatment. All patients recovered within 10 days. The species was identified as Amanita pseudosychnopyramis, and its contents of muscarine, muscimol and ibotenic acid were 170.3 ± 5.9 mg/kg, 835.4 ± 43.1 mg/kg and 637.9 ± 54.8 mg/kg in dry weight, respectively, as detected by ultrahigh-performance liquid chromatography tandem mass spectrometry (UPLC–MS/MS). To our knowledge, this is the first report of Amanita pseudosychnopyramis poisoning worldwide. [Display omitted] •This is the first report of Amanita pseudosychnopyramis poisoning worldwide.•Muscarine, ibotenic acid and muscimol were identified in Amanita pseudopsycnopyramis.•The detailed case information about critically ill patients was collected.
ISSN:0041-0101
1879-3150
DOI:10.1016/j.toxicon.2022.04.001