In vitro use of standard fluid infusion central venous catheter for slow continuous ultrafiltration feasibility assessment

Background Slow continuous ultrafiltration (SCUF) by central venous catheter (CVC) for hemodialysis is a simple extracorporeal ultrafiltration that can reduce and control fluid overload in patients with chronic or acute chronic heart failure unresponsive to medical therapy. In order to avoid complic...

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Bibliographic Details
Published in:Artificial organs 2022-08, Vol.46 (8), p.1695-1700
Main Authors: Nalesso, Federico, Garzotto, Francesco, Gobbi, Laura, Cattarin, Leda, Calò, Lorenzo A.
Format: Article
Language:English
Subjects:
Blood flow
Catheters
central venous catheter
chronic heart failure
Complications
Congestive heart failure
Feasibility studies
fluid overload
Heart failure
Hemodialysis
Intensive care
Lumens
Medical equipment
Medical instruments
Patients
Placement
slow continuous ultrafiltration
Technology assessment
Ultrafiltration
Weight loss
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Summary:Background Slow continuous ultrafiltration (SCUF) by central venous catheter (CVC) for hemodialysis is a simple extracorporeal ultrafiltration that can reduce and control fluid overload in patients with chronic or acute chronic heart failure unresponsive to medical therapy. In order to avoid complications and risks related to the catheterization with a standard CVC for hemodialysis to provide the SCUF, considering that hospitalized patients affected by congestive heart failure commonly undergo CVC placement for medications delivering, we tested an in vitro model to use a standard CVC for infusion to perform SCUF. Methods We performed an in vitro SCUF experimental model through two different lumens of a triple (8Fr × 20 cm Tri‐lumen catheter Kit—Envans Extra) and a quad‐lumen CVC (8.5Fr × 20 cm Quad‐lumen catheter kit—Benefis Medical Devices) commonly used in our Intensive Care Unit for fluids and medications infusions. We used Prismaflex with the HF‐20 set (Baxter, IL, USA) to perform the SCUF treatment. Results Our in vitro data confirm the technical feasibility of the use of standard CVC for fluid infusion to perform a SCUF treatment with a theoretical weight loss of up to 200 ml/h by a blood flow ranging from 30 to 45 ml/min. Conclusions The use of standard infusion CVC could be utilized in the intensive care unit to perform SCUF not exposing patients to the risks and complications related to the placement and permanence of CVC for hemodialysis. Slow continuous ultrafiltration (SCUF) by central venous catheter (CVC) for hemodialysis can reduce and control fluid overload in patients with heart failure. To avoid complications and risks related to the CVC for hemodialysis placement to provide the SCUF, we tested an in vitro model to use a standard CVC for infusion to perform SCUF through two different lumens of a standard triple and a quad‐lumen CVC. Our results demonstrated the feasibility of the infusion CVC to perform SCUF.
ISSN:0160-564X
1525-1594
DOI:10.1111/aor.14253