Impact of diabetes on outcomes in breast reconstruction: A systematic review and meta-analysis

As rates of breast cancer and type II diabetes increase, so does the number of women with diabetes undergoing breast reconstruction (BR). Patients with diabetes are at increased risk of postoperative complications. This meta-analysis seeks to evaluate the post-operative outcomes of women with diabet...

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Bibliographic Details
Published in:Journal of plastic, reconstructive & aesthetic surgery reconstructive & aesthetic surgery, 2022-06, Vol.75 (6), p.1793-1804
Main Authors: Liu, Qinxin, Aggarwal, Ayushi, Wu, Mengfan, Darwish, Oliver A., Baldino, Kodi, Haug, Valentin, Agha, Riaz A., Orgill, Dennis P., Panayi, Adriana C.
Format: Article
Language:English
Subjects:
Breast reconstruction
Diabetes
Mastectomy
Surgical outcomes
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Summary:As rates of breast cancer and type II diabetes increase, so does the number of women with diabetes undergoing breast reconstruction (BR). Patients with diabetes are at increased risk of postoperative complications. This meta-analysis seeks to evaluate the post-operative outcomes of women with diabetes who underwent BR following mastectomy. This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The EMBASE, PUBMED, and MEDLINE electronic databases were searched from inception to November 1, 2020 for studies published in English. Outcomes evaluated were overall complications, surgical complications, and longer hospital stay. Subgroup analysis investigated outcomes, such as implant/flap failure, infection, and necrosis. Sixty-five studies met our inclusion criteria and 38 provided data to be included in the meta-analysis. A total of 151,585 patients were included, of which 9299 had diabetes. Women with diabetes were more likely to experience overall complications (11.6% vs 5.6%; p
ISSN:1748-6815
1878-0539
DOI:10.1016/j.bjps.2022.02.053