Factors determining the response to treatment in patients with vestibular migraine

To find out clinical features associated with poor response to treatment in vestibular migraine (VM) VM patients treated with drugs recommended in migraine prophylaxis were included in this multicenter study. Migraine features including type, age of onset of headache and vertigo attacks, attack freq...

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Published in:Neurological research (New York) 2022-09, Vol.44 (9), p.847-854
Main Authors: Kısabay Ak, Ayşın, Çelebisoy, Neşe, Özdemir, Hüseyin Nezih, Gökçay, Figen, Saruhan Durmaz, Gülsüm, Top Kartı, Dilek, Ertaşoğlu Toydemir, Hülya, Yayla, Vildan, Çolpak  Işıkay, Ayşe İlksen, Erkent, İrem, Özçelik, Pınar, Akdal, Gülden, Ataç, Ceyla, Bıçakcı, Şebnem, Ozaydın-Göksu, Eylem, Güleç Uyaroğlu, Feray
Format: Article
Language:English
Subjects:
allodynia
anxiety/depression
dizziness/imbalance
treatment
Vestibular migraine
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Summary:To find out clinical features associated with poor response to treatment in vestibular migraine (VM) VM patients treated with drugs recommended in migraine prophylaxis were included in this multicenter study. Migraine features including type, age of onset of headache and vertigo attacks, attack frequency, intensity, associated symptoms, triggering factors, presence of interictal dizziness/imbalance, anxiety, depression, history of motion sickness, and family history of migraine were noted. Amitriptyline, flunarizine, propranolol, topiramate and venlafaxine were chosen depending on patients' individual requirements. Maximum dose of each drug was tried for 2 months to decide its efficacy. In the case of inefficacy, it was changed with another preventive drug of different class. If there was still no improvement, two drugs of different classes were combined. ≥ 50% reduction in attack frequency and severity in patients using one drug and a combination of two drugs was compared, with patients showing
ISSN:0161-6412
1743-1328
DOI:10.1080/01616412.2022.2056341