Risk factors for incomplete excision of cutaneous squamous cell carcinoma: a large cohort study

Background The standard treatment for cutaneous squamous cell carcinoma (cSCC) is surgical excision. Failure to radically remove a cSCC is a risk for recurrence, progression and metastasis. Objectives This study investigates several risk factors for incomplete excision of cSCC. Methods All consecuti...

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Bibliographic Details
Published in:Journal of the European Academy of Dermatology and Venereology 2022-08, Vol.36 (8), p.1229-1234
Main Authors: Marsidi, N., Ottevanger, R., Bouwes Bavinck, J.N., Krekel ‐ Taminiau, N.M.A., Goeman, J.J., Genders, R.E.
Format: Article
Language:English
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Summary:Background The standard treatment for cutaneous squamous cell carcinoma (cSCC) is surgical excision. Failure to radically remove a cSCC is a risk for recurrence, progression and metastasis. Objectives This study investigates several risk factors for incomplete excision of cSCC. Methods All consecutive patients in a single institution treated with wide local excision for primary cSCC over a 10‐year period were included in this study. Risk factors such as: gender, age, immunosuppression, tumour size, location, differentiation grade, tumour depth, perineural and lymphovascular invasion (PNI and LVI) were extracted from the database. Univariable and (if applicable) multivariable logistic regression analysis were used to identify risk factors (P 
ISSN:0926-9959
1468-3083
DOI:10.1111/jdv.18101