Charlson Comorbidity Index is Associated With Longer-Term Mortality and Re-Admissions Following Coronary Artery Bypass Grafting

The Charlson Comorbidity Index (CCI) is widely utilized for risk stratification by providers, payors, and administrative database researchers for non-cardiac surgical patients. CCI scores have not been validated in cardiac surgical patients. We hypothesize that the CCI will predict mid-term mortalit...

Full description

Saved in:
Bibliographic Details
Published in:The Journal of surgical research 2022-07, Vol.275, p.300-307
Main Authors: Coyan, Garrett N., Chin, Hannah, Shah, Ayesha, Miguelino, Alyssa M., Wang, Yisi, Kilic, Arman, Sultan, Ibrahim, Sciortino, Christopher M., Chu, Danny
Format: Article
Language:English
Subjects:
Cardiac surgery
Cardiac Surgical Procedures
Charlson comorbidity index
Comorbidity
Coronary Artery Bypass - adverse effects
Coronary artery bypass grafting
Humans
Proportional Hazards Models
Retrospective Studies
Risk Factors
Risk scores
Risk stratification
ROC Curve
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The Charlson Comorbidity Index (CCI) is widely utilized for risk stratification by providers, payors, and administrative database researchers for non-cardiac surgical patients. CCI scores have not been validated in cardiac surgical patients. We hypothesize that the CCI will predict mid-term mortality and re-admissions, but performance may be different than purpose-built cardiac surgery risk calculators. Patients undergoing isolated CABG between 2011 and 2017 were reviewed. Age-adjusted CCI scores were calculated based on clinical status at a time of index operation using prospectively captured data from institutional databases. Primary endpoint was 5-year mortality and 1-year re-admissions. The CCI, STS predicted mortality, and ASCERT 5-year mortality scores were compared in a sub-cohort of 500 patients. Patients underwent analysis using Cox Proportional Hazard ratios, Kaplan–Meier analysis, and ROC comparisons. Average CCI score for the overall population (n = 6064) was 3.40 ± 1.75. Kaplan–Meier analysis revealed significant difference in mortality stratified by CCI. Hazard ratio for 5-year mortality increased with each interval increase in CCI score value (HR 1.38 [1.33-1.43], P 
ISSN:0022-4804
1095-8673
DOI:10.1016/j.jss.2022.02.012