Factors Associated with Bone Erosion in Patients with Gout: A Dual-Energy Gemstone Spectral Imaging Computed Tomography Study

This study aimed to assess the factors influencing bone erosion in patients with gout using dual-energy gemstone spectral imaging CT. We compared the clinical data, laboratory indices, and tissue urate levels at the monosodium urate (MSU)-bone interface measured by dual-energy gemstone spectral imag...

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Bibliographic Details
Published in:Modern rheumatology 2022-10, Vol.32 (6), p.1170-1174
Main Authors: Liu, Xiaofei, Zhang, Xiaohuan, Mo, Shiyan, Liang, Dongfeng, Li, Baige, Zhu, Jian
Format: Article
Language:English
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Summary:This study aimed to assess the factors influencing bone erosion in patients with gout using dual-energy gemstone spectral imaging CT. We compared the clinical data, laboratory indices, and tissue urate levels at the monosodium urate (MSU)-bone interface measured by dual-energy gemstone spectral imaging computed tomography of 87 gout patients with (n=41) and without (n=46) bone erosion. Logistic regression analysis was used to investigate the risk factors associated with bone erosion. In total, 47.1% of patients with gout had bone erosion. The disease duration, serum uric acid, tissue urate levels, and the presence of tophi were significantly higher (p
ISSN:1439-7595
1439-7609
DOI:10.1093/mr/roab116