Atrial fibrillation and stroke: A review and new insights

The link between heart and brain continues to be a matter of great interest for the scientific community. One of the most established associations between the two is that the heart is a significant source of emboli and is responsible for 20-25% of all ischemic strokes. The most frequent underlying c...

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Bibliographic Details
Published in:Trends in cardiovascular medicine 2023-01, Vol.33 (1), p.23-29
Main Authors: Escudero-Martínez, Irene, Morales-Caba, Lluis, Segura, Tomás
Format: Article
Language:English
Subjects:
Atrial fibrillation
Atrial Fibrillation - diagnosis
Atrial Fibrillation - epidemiology
Atrial Fibrillation - therapy
Brain Ischemia - epidemiology
Embolism
Humans
Incidence
Ischemic stroke
Prevention
Risk Factors
Stroke - diagnosis
Stroke - epidemiology
Stroke - etiology
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Summary:The link between heart and brain continues to be a matter of great interest for the scientific community. One of the most established associations between the two is that the heart is a significant source of emboli and is responsible for 20-25% of all ischemic strokes. The most frequent underlying cause of cardioembolic stroke is atrial fibrillation (AF), a disease that affects almost 3 million people in the USA and 4.5 million in Europe. AF increases the risk of ischemic stroke by a factor of 3 to 5 times. It is estimated that AF is responsible for 15% of all strokes worldwide. A more comprehensive understanding of this association and development of intensive stroke prevention measures are needed, as we know that AF incidence and prevalence will increase over the coming years, becoming one of the largest epidemics and public health challenges we face.
ISSN:1050-1738
1873-2615
DOI:10.1016/j.tcm.2021.12.001