Effects of blood withdrawal on cardiac, hemodynamic, and pulmonary responses to a moderate acute workload in healthy middle-aged and older females

To investigate the effects of blood withdrawal on cardiac, hemodynamic, and pulmonary responses to submaximal exercise in females. 30 healthy females (63.8 ± 8.3 years) were recruited for this experimental study. Transthoracic echocardiography, non-invasive blood pressure monitoring, and oxygen upta...

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Bibliographic Details
Published in:Journal of science and medicine in sport 2022-03, Vol.25 (3), p.198-203
Main Authors: Pentz, Brandon, Diaz-Canestro, Candela, Sehgal, Arshia, Montero, David
Format: Article
Language:English
Subjects:
Aerobic capacity
Aged
Blood Pressure
Blood volume
Cardiac Output
Exercise
Female
Females
Heart
Heart rate
Heart Rate - physiology
Hematology
Hemodynamics - physiology
Hemoglobin
Humans
Laboratories
Males
Middle age
Middle Aged
Neuromuscular diseases
Physical fitness
Stroke volume
Stroke Volume - physiology
Workload
Workloads
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Summary:To investigate the effects of blood withdrawal on cardiac, hemodynamic, and pulmonary responses to submaximal exercise in females. 30 healthy females (63.8 ± 8.3 years) were recruited for this experimental study. Transthoracic echocardiography, non-invasive blood pressure monitoring, and oxygen uptake were assessed during a fixed submaximal workload (100 W) prior to (day 1) and immediately after (day 2) a 10% reduction of blood volume. Main measurements included left ventricular end-diastolic volume, stroke volume, cardiac output, mean arterial pressure, systolic blood pressure, diastolic blood pressure, and oxygen uptake. Blood volume was determined via carbon monoxide rebreathing. Participant's blood volume ranged from 3.8 to 6.6 L. Following 10% reduction in blood volume (0.5 ± 0.1 L), left ventricular end-diastolic volume (p ≤ 0.030) and stroke volume (p 
ISSN:1440-2440
1878-1861
DOI:10.1016/j.jsams.2021.10.012