Fasting plasma glucose level to guide the need for an OGTT to screen for gestational diabetes mellitus

Aims To determine the fasting plasma glucose (FPG) level at which an oral glucose tolerance test (OGTT) could be avoided to screen for gestational diabetes (GDM) and to evaluate the characteristics of women across this FPG threshold. Methods A multi-centric prospective cohort study with 1843 women r...

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Bibliographic Details
Published in:Acta diabetologica 2022-03, Vol.59 (3), p.381-394
Main Authors: Beunen, Kaat, Neys, Astrid, Van Crombrugge, Paul, Moyson, Carolien, Verhaeghe, Johan, Vandeginste, Sofie, Verlaenen, Hilde, Vercammen, Chris, Maes, Toon, Dufraimont, Els, Roggen, Nele, De Block, Christophe, Jacquemyn, Yves, Mekahli, Farah, De Clippel, Katrien, Van Den Bruel, Annick, Loccufier, Anne, Laenen, Annouschka, Devlieger, Roland, Mathieu, Chantal, Benhalima, Katrien
Format: Article
Language:English
Subjects:
Beta cells
Blood Glucose - metabolism
Diabetes
Diabetes mellitus
Diabetes, Gestational - diagnosis
Diabetes, Gestational - epidemiology
Fasting
Female
Fetal Macrosomia
Fetuses
Gestational age
Gestational diabetes
Glucose
Glucose tolerance
Glucose Tolerance Test
Humans
Insulin
Insulin resistance
Internal Medicine
Laboratory testing
Medicine
Medicine & Public Health
Metabolic Diseases
Original Article
Pregnancy
Pregnancy and diabetes
Prospective Studies
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Summary:Aims To determine the fasting plasma glucose (FPG) level at which an oral glucose tolerance test (OGTT) could be avoided to screen for gestational diabetes (GDM) and to evaluate the characteristics of women across this FPG threshold. Methods A multi-centric prospective cohort study with 1843 women receiving universal screening for GDM with a 75 g OGTT. Results In the total population, GDM prevalence was 12.5% (231). A FPG 
ISSN:0940-5429
1432-5233
DOI:10.1007/s00592-021-01812-9