Simplified Academic Research Consortium for High Bleeding Risk (ARC-HBR) Definition Predicts Bleeding Events in Patients With Heart Failure

Background:It has recently been reported that the simplified Academic Research Consortium for High Bleeding Risk (ARC-HBR) definition, which excludes 6 rare criteria, is comparable to the original ARC-HBR definition in predicting major bleeding in patients with coronary artery disease (CAD) who unde...

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Published in:	Circulation Journal 2021/12/24, Vol.86(1), pp.147-155
Main Authors:	Sato, Yu, Yoshihisa, Akiomi, Takeishi, Ryohei, Ohara, Himika, Sugawara, Yukiko, Ichijo, Yasuhiro, Hotsuki, Yu, Watanabe, Koichiro, Abe, Satoshi, Misaka, Tomofumi, Sato, Takamasa, Oikawa, Masayoshi, Kobayashi, Atsushi, Nakazato, Kazuhiko, Takeishi, Yasuchika
Format:	Article
Language:	eng
Subjects:	Aftercare Gastrointestinal bleeding Gastrointestinal Hemorrhage - diagnosis Gastrointestinal Hemorrhage - epidemiology Gastrointestinal Hemorrhage - etiology Heart Failure - complications Heart Failure - diagnosis Hemorrhage Hemorrhagic stroke High bleeding risk Humans Patient Discharge Percutaneous Coronary Intervention - adverse effects Platelet Aggregation Inhibitors - adverse effects Risk Assessment Risk Factors Treatment Outcome
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Summary:	Background:It has recently been reported that the simplified Academic Research Consortium for High Bleeding Risk (ARC-HBR) definition, which excludes 6 rare criteria, is comparable to the original ARC-HBR definition in predicting major bleeding in patients with coronary artery disease (CAD) who undergo percutaneous coronary intervention. In this study, we investigated whether the simplified ARC-HBR definition could be applied to patients with heart failure (HF) to identify those at high bleeding risk (HBR).Methods and Results:In all, 2,437 patients hospitalized for HF were enrolled in this study. Patients were divided into 2 groups based on the simplified ARC-HBR definition: those at HBR (n=2,026; 83.1%) and those not (non-HBR group; n=411; 16.9%). The HBR group was older (72.0 vs. 61.0 years; P
ISSN:	1346-9843 1347-4820