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Validation of McCluskey Index for Massive Blood Transfusion Prediction in Liver Transplantation
•The McCluskey index is a good indicator of the risk of hemorrhage.•Our study shows a noticeable reduction in patient survival in the higher risk groups of McCluskey.•The McCluskey index is a good indicator the necessity of massive blood transfusion in liver transplantation. The McCluskey index has...
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Published in: | Transplantation proceedings 2021-11, Vol.53 (9), p.2698-2701 |
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Main Authors: | , , , , , , , , , , |
Format: | Article |
Language: | English |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | •The McCluskey index is a good indicator of the risk of hemorrhage.•Our study shows a noticeable reduction in patient survival in the higher risk groups of McCluskey.•The McCluskey index is a good indicator the necessity of massive blood transfusion in liver transplantation.
The McCluskey index has been used as a tool to predict massive bleeding (>6 red blood cells units) during orthotropic liver transplantation. The objective of this study is to verify its efficacy at our institution.
Between May 1998 and December 2017, we performed 1216 orthotropic liver transplantations, of which 1016 had sufficient data registered with respect to hemoderivative transfusion. We divided these patients into groups based on the original study of McCluskey. This study was approved by the ethical committee of our Institution and was performed in accordance with the Declaration of Helsinki.
The mean Model for End-Stage Liver Disease score in the 4 groups was 7.5 (range, 7-8) for low risk; 13 (range, 3-32) for medium risk, 17 (range, 8-41) for high risk, and 25 (range, 11-36) for very high risk (P < .001). No significant differences were observed regarding body mass index or hospital stay. No differences have been found in the number of suboptimal donors among the groups. With respect to hemoderivative transfusions, we observed the following for red blood cells: 7 (range, 6-8) units for low risk; 5.5 (range, 0-74) for medium risk; 7 (range, 0-73) for high risk, and 12 (range, 5-30) for very high risk (P < .001) and transfusion of plasma: 12 (range, 10-15) units for low risk; 11 (range, 0-89) for medium risk; 14 (range, 0-76) for high risk, and 13 (range, 3-30) for very high risk (P = .001).
The McCluskey index is a good indicator of the risk of hemorrhage and hence the necessity of transfusion. |
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ISSN: | 0041-1345 1873-2623 |
DOI: | 10.1016/j.transproceed.2021.04.022 |