Cost-effectiveness of the adherence with recommendations for clinical monitoring of patients with diabetes

To validate a set of indicators for monitoring the quality of care of patients with diabetes in ‘real-life’ practice through its relationship with measurable clinical outcomes and healthcare costs. A population-based cohort study was carried out by including the 20,635 patients, residents in the Lom...

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Published in:Nutrition, metabolism, and cardiovascular diseases metabolism, and cardiovascular diseases, 2021-10, Vol.31 (11), p.3111-3121
Main Authors: Corrao, Giovanni, Rea, Federico, Mancia, Giuseppe, Perseghin, Gianluca, Merlino, Luca, Martini, Nello, Carbone, Simona, Carle, Flavia, Bucci, Andrea, Dajko, Marianxhela, Arcà, Silvia, Bellentani, Donata, Bruno, Velia, Ceccolini, Carla, De Feo, Angela, Lispi, Lucia, Mariniello, Rosanna, Masullo, Maurizio, Medici, Federica, Pisanti, Paola, Visca, Modesta, Zanini, Rinaldo, Di Fiandra, Teresa, Magliocchetti, Natalia, Romano, Giovanna, Cantarutti, Anna, Pugni, Pietro, Davoli, Marina, Di Martino, Mirko, Lallo, Adele, Vittori, Patrizia, Vuillermin, Giuliana, Bernardo, Alfonso, Fusciante, Anna, Belotti, Laura, De Palma, Rossana, Di Felice, Enza, Chiandetti, Roberta, Clagnan, Elena, Del Zotto, Stefania, Di Lenarda, Andrea, Mariotto, Aldo, Prezza, Marisa, Zanier, Loris, Fusco, Danilo, Marinacci, Chiara, Lora, Antonio, Spazzafumo, Liana, Pizzi, Simone, Simiele, Maria, Massaro, Giuseppe, Attolini, Ettore, Lepore, Vito, Petrarolo, Vito, De Luca, Giovanni, Fantaci, Giovanna, Pollina Addario, Sebastiano, Scondotto, Salvatore, Bellomo, Francesco, Braga, Mario, Di Fabrizio, Valeria, Forni, Silvia, Francesconi, Paolo, Profili, Francesco, Avossa, Francesco, Corradin, Matteo, Vigna, Silvia, Dondi, Letizia, Pedrini, Antonella, Piccinni, Carlo, Cosentino, Mimma, Marvulli, Maria G., Maggioni, Aldo
Format: Article
Language:English
Subjects:
Complications
Cost-effectiveness
Diabetes
Healthcare cost
Incremental cost-effectiveness ratio
Periodic examinations
Population-based cohort study
Real-world
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Summary:To validate a set of indicators for monitoring the quality of care of patients with diabetes in ‘real-life’ practice through its relationship with measurable clinical outcomes and healthcare costs. A population-based cohort study was carried out by including the 20,635 patients, residents in the Lombardy Region (Italy), who in the year 2012 were newly taken-in-care for diabetes. Adherence with clinical recommendations (i.e., controls for glycated haemoglobin, lipid profile, urine albumin excretion and serum creatinine) was recorded during the first year after the patient was taken-in-care, and categorized according whether he/she complied with none or almost none (0 or 1), just some (2) or all or almost all (3 or 4) the recommendations, respectively denoted as poor, intermediate and high adherence. Short- and long-term complications of diabetes, and healthcare cost incurred by the National Health Service, were assessed during follow-up. Compared with patients with poor adherence, those with intermediate and high adherence respectively showed (i) a delay in outcome occurrence of 13 days (95% CI, −2 to 27) and 23 days (9–38), and (ii) a lower healthcare cost of 54 € and 77 €. In average, a gain of 18 Euros and 15 Euros for each day free from diabetic complication by increasing adherence respectively from poor to intermediate and from poor to high were observed. Close control of patients with diabetes through regular clinical examinations must be considered the cornerstone of national guidance, national audits, and quality improvement incentive schemes. •The management of diabetes remains sub-optimal in ‘real-life’ practice.•Adherence with clinical recommendations reduces harmful outcomes and costs.•The economic benefit is greatest among frail patients.
ISSN:0939-4753
1590-3729
DOI:10.1016/j.numecd.2021.07.014