Does sodium thiosulphate avoid the formation of the brown‐coloured precipitate as an intermediate irrigant between NaOCl and chlorhexidine?

This study evaluated the efficacy of sodium thiosulphate (ST) as an intermediate irrigant between sodium hypochlorite (NaOCl) and chlorhexidine (CHX) to avoid the formation of the brown‐coloured precipitate. The in vitro experiment used microtubes to test the mixture of 2.5% NaOCl, 2% CHX and 5% ST...

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Published in:Australian endodontic journal 2022-04, Vol.48 (1), p.72-76
Main Authors: Alberto, Amanda Pereira Leite, Oliveira, Diogo da Silva, Oliveira, Henrique Eduardo, Maciel, Ana Carolina de Carvalho, Belladonna, Felipe Gonçalves, Silva, Emmanuel João Nogueira Leal da
Format: Article
Language:English
Subjects:
Animals
Cattle
Chemical Precipitation
Chlorhexidine
Chlorhexidine - pharmacology
Endodontics
Experiments
para‐chloroaniline
Root Canal Irrigants
Sodium hypochlorite
Sodium Hypochlorite - pharmacology
Sodium thiosulfate
sodium thiosulphate
Thiosulfates
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Summary:This study evaluated the efficacy of sodium thiosulphate (ST) as an intermediate irrigant between sodium hypochlorite (NaOCl) and chlorhexidine (CHX) to avoid the formation of the brown‐coloured precipitate. The in vitro experiment used microtubes to test the mixture of 2.5% NaOCl, 2% CHX and 5% ST solutions, varying their order and time of addition. In the ex vivo experiment, 10 bovine teeth were divided into two groups according to the intermediate irrigant used: distilled water (control) and 5% ST (experimental). Colour change occurred in all microtubes after interaction between solutions. While the precipitate was not observed in the experimental group, it was seen in all specimens of the control group. The 5% ST was able to prevent the formation of the brown‐coloured precipitate in the ex vivo experiment, whereas it only prevented its in vitro formation when the waiting time for adding CHX was 10, 15 and 20 min.
ISSN:1329-1947
1747-4477
DOI:10.1111/aej.12562