Graphene and Carbon Nanotube‐based Electrochemical Sensing Platforms for Dopamine

Dopamine (DA) is an important neurotransmitter, which is created and released from the central nervous system. It plays a crucial role in human activities, like cognition, emotions, and response to anything. Maladjustment of DA in human blood serum results in different neural diseases, like Parkinso...

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Bibliographic Details
Published in:Chemistry, an Asian journal an Asian journal, 2021-11, Vol.16 (22), p.3516-3543
Main Authors: Islam, Santa, Shaheen Shah, Syed, Naher, Shamsun, Ali Ehsan, Muhammad, Aziz, Md. Abdul, Ahammad, A. J. Saleh
Format: Article
Language:English
Subjects:
carbon nanotubes
Dopamine
Dopamine - analysis
electrochemical detection
Electrochemical Techniques
graphene
Graphite - chemistry
Humans
nanocomposites
Nanotubes, Carbon - chemistry
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Summary:Dopamine (DA) is an important neurotransmitter, which is created and released from the central nervous system. It plays a crucial role in human activities, like cognition, emotions, and response to anything. Maladjustment of DA in human blood serum results in different neural diseases, like Parkinson's and Schizophrenia. Consequently, researchers have started working on DA detection in blood serum, which is undoubtedly a hot research area. Electrochemical sensing techniques are more promising to detect DA in real samples. However, utilizing conventional electrodes for selective determination of DA encounters numerous problems due to the coexistence of other materials, such as uric acid and ascorbic acid, which have an oxidation potential close to DA. To overcome such problems, researchers have put their focus on the modification of bare electrodes. The aim of this review is to present recent advances in modifications of most used bare electrodes with carbonaceous materials, especially graphene, its derivatives, and carbon nanotubes, for electrochemical detection of DA. A brief discussion about the mechanistic phenomena at the electrode interface has also been included in this review. Dopamine (DA) is a critical neurotransmitter, created and released from the central nervous system. The aim of this review is to present recent advances in modifications of most used bare electrodes with carbonaceous materials, especially graphene, its derivatives, and carbon nanotubes, for electrochemical detection of DA.
ISSN:1861-4728
1861-471X
DOI:10.1002/asia.202100898