Experience with endoscopic submucosal dissection for the treatment of early neoplasms of the digestive tract

BACKGROUNDEndoscopic submucosal dissection (ESD) allows en-bloc resection of early gastro-intestinal neoplasms (EGIN) with healing potential. AIMTo describe the results of patients treated with ESD for EGIN by our team. PATIENTS AND METHODSDescriptive study of patients with EGIN who underwent ESD wi...

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Bibliographic Details
Published in:Revista medíca de Chile 2021-04, Vol.149 (4), p.501-507
Main Authors: Mejía, Ricardo, Sáez, Josefina, Briones, Pamela, Norero, Enrique, Ceroni, Marco, Díaz, Alfonso, Sharp, Allan
Format: Article
Language:Spanish
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Summary:BACKGROUNDEndoscopic submucosal dissection (ESD) allows en-bloc resection of early gastro-intestinal neoplasms (EGIN) with healing potential. AIMTo describe the results of patients treated with ESD for EGIN by our team. PATIENTS AND METHODSDescriptive study of patients with EGIN who underwent ESD with curative intention between January 2008 and March 2020. RESULTSOne hundred thirty-two ESD were performed in 127 patients. 77% were gastric lesions, 14% colorectal, 8% esophageal and 1% duodenal. En-bloc resection was achieved in 98.4% of ESDs. Eighty eight percent of patients met curative standards. Overall, cancer-specific, and recurrence-free survival were 95%, 100% and 98% respectively. CONCLUSIONSESD allows en-bloc resections with curative potential in selected patients, but with a significant reduction in morbidity and mortality and less impact on quality of life. Our results suggest the feasibility to perform ESD in our country with results comparable to those reported in the literature.
ISSN:0717-6163
DOI:10.4067/s0034-98872021000400501