Age, American Thyroid Association Risk Group, and Response to Therapy Are Prognostic Factors in Children With Differentiated Thyroid Cancer

Against the background of increasing incidence, pediatric differentiated thyroid carcinoma (DTC) frequently presents with advanced disease and high recurrence rates while prognosis remains excellent. We investigated the use of a pediatric classification and an adult response to therapy risk stratifi...

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Bibliographic Details
Published in:The journal of clinical endocrinology and metabolism 2022-01, Vol.107 (1), p.e165-e177
Main Authors: Redlich, Antje, Luster, Markus, Lorenz, Kerstin, Lessel, Lienhard, Rohrer, Tilman R, Schmid, Kurt W, Frühwald, Michael C, Vorwerk, Peter, Kuhlen, Michaela
Format: Article
Language:English
Subjects:
Adenocarcinoma - pathology
Adenocarcinoma - surgery
Adolescent
Age Factors
Associations, institutions, etc
Care and treatment
Child
Child, Preschool
Children
Diseases
Female
Follow-Up Studies
Health aspects
Humans
Infant
Infant, Newborn
Male
Metastasis
Neoplasm Recurrence, Local - pathology
Neoplasm Recurrence, Local - surgery
Pediatrics
Prognosis
Relapse
Retrospective Studies
Risk Assessment - methods
Risk Factors
Societies
Survival Rate
Thyroid cancer
Thyroid Neoplasms - pathology
Thyroid Neoplasms - surgery
Thyroidectomy - mortality
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Description
Summary:Against the background of increasing incidence, pediatric differentiated thyroid carcinoma (DTC) frequently presents with advanced disease and high recurrence rates while prognosis remains excellent. We investigated the use of a pediatric classification and an adult response to therapy risk stratification for pediatric DTC patients and their implications for adaptation of treatment and follow-up. Data from patients aged
ISSN:0021-972X
1945-7197
DOI:10.1210/clinem/dgab622