The Effect of Sex on Door-to-Balloon Time in Patients Presenting With ST-Elevation Myocardial Infarction and Referred for Primary Percutaneous Coronary Intervention: A Systematic Review

Timely reperfusion using primary percutaneous coronary intervention (pPCI) is the cornerstone of acute ST-elevation myocardial infarction (STEMI) management. We conducted a systematic review to examine the effect of sex on door-to-balloon (D2B) time and symptom-to-balloon (S2B) time. We observed lon...

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Bibliographic Details
Published in:Cardiovascular revascularization medicine 2022-04, Vol.37, p.120-127
Main Authors: Babiolakis, Corinne S., Sharma, Shubham, Sayed, Nawid, Abunassar, Joseph G., Haseeb, Sohaib, Abuzeid, Wael
Format: Article
Language:English
Subjects:
Door-to-balloon time
Female
Humans
Male
Percutaneous Coronary Intervention
Sex
ST Elevation Myocardial Infarction - diagnostic imaging
ST Elevation Myocardial Infarction - therapy
ST-elevation myocardial infarction
Symptom-to-balloon time
Time Factors
Treatment Outcome
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Summary:Timely reperfusion using primary percutaneous coronary intervention (pPCI) is the cornerstone of acute ST-elevation myocardial infarction (STEMI) management. We conducted a systematic review to examine the effect of sex on door-to-balloon (D2B) time and symptom-to-balloon (S2B) time. We observed longer D2B times and S2B times in female patients presenting with STEMI and referred for pPCI when compared to male patients. Future work is required to try and elucidate and mitigate sex-based front-line treatment delays for female STEMI patients. •Timely reperfusion is the cornerstone of acute STEMI management.•Most (91%) included studies reflected longer D2B times for females vs. males.•Most (96%) included studies reflected longer S2B times for females vs. males.•Total ischemic time (not just hospital-based ischemic time) is important to consider.
ISSN:1553-8389
1878-0938
DOI:10.1016/j.carrev.2021.07.011